Publications

5808 Results

Leveraging population admixture to explain missing heritability of complex traits

Authors
N Zaitlen;B Pasaniuc;S Sankararaman;G Bhatia;J Zhang;A Gusev;T Young;A Tandon;S Pollack;B Vilhjalmsson;TL Assimes;SI Berndt;WJ Blot;S Chanock;N Francedschini;P Goodman;J He;A Hennis;A Hsing;S Ingles;W Isaacs;R Kittles;EA Klein;L Lange;B Nemesure;N Patterson;D Reich;B Rybicki;J Stanford;V Stevens;S Strom;E Whitsel;J Witte;J Xu;C Haiman;C Kooperberg;D Stram;A Reiner;H Tang;A Price
Journal / Conference
Nature Genetics 46(12):1356-1362;
Year
2014
Research Committee(s)
Prevention, Screening, and and Surveillance
PMID
PMID25383972
PMC
PMC4244251
Study Number(s)
S0000

A randomized phase II study of azacitidine combined with lenalidomide or with vorinostat vs. azacitidine monotherapy in higher-risk myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML): North American Intergroup study SWOG S1117

Authors
M Sekeres;M Othus;AF List;O Odenike;RM Stone;S Gore;M Litzow;R Buckstein;M Velasco;R Gaur;E Attallah;EC Attar;FR Appelbaum;HP Erba
Journal / Conference
Blood 124(21):LBA-5; American Society for Hematology (December 6-9, 2014, San Francisco, CA), LBA, oral;
Year
2014
Research Committee(s)
Leukemia
Study Number(s)
S1117

Randomized comparison of adjuvant tamoxifen (T) plus ovarian function suppression (OFS) versus tamoxifen in premenopausal women with hormone receptor-positive (HR+) early breast cancer (BC): analysis of the SOFT trial

Authors
P Francis;M Regan;G Fleming;I Lang;E Ciruelos;M Bellet;H Bonnefoi;M Climent;L Pavesi;H Burstein;S Martino;NE Davidson;CE Geyer;B Walley;RE Coleman;P Kerbrat;M Rabaglio-Poretti;AS Coates;A Goldhirsch;RD Gelber
Journal / Conference
San Antonio Breast Cancer Symposium Annual Meeting (December 9-13, 2014, San Antonio, TX),abstr. [S3-08], oral presentation;
Year
2014
Research Committee(s)
Breast

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

Authors
AA Al Olama;Z Kote-Jarai;DV Conti;F Schumacher;Y Han;S Benloch;DJ Hazelett;Z Wang;E Saunders;D Leongamornlert;S Lindstrom;S Jugurnauth-Little;T Dadaev;M Tymrakiewicz;DO Stram;X Sheng;LC Pooler;K Park;L Xia;J Tyrer;LN Kolonel;L Le Marchand;RN Hoover;MJ Machiela;M Yeager;L Burdette;C Chung;A Hutchinson;K Yu;C Goh;M Ahmed;K Govindasami;M Guy;TL Tammela;A Auvinen;T Wahlfors;J Schleutker;T Visakorpi;KA Keinonen;J Xu;M Aly;J Donovan;RC Travis;TJ Key;A Siddiq;F Canzian;KT Khaw;A Takahashi;M Kubo;P Pharoah;N Pashayan;M Weischer;BG Nordestgaard;SF Nielsen;P Klarskov;MA Roder;P Iversen;SN Thibodeau;SK McDonnell;DJ Schaid;JL Stanford;S Kolb;S Holt;B Knudsen;AH Coll;SM Gapstur;WR Diver;VL Stevens;C Maier;M Luedeke;K Herkommer;AE Rinckleb;SS Strom;C Pettaway;ED Yeboah;Y Tettey;RB Biritwum;A Adjei;E Tay;A Truelove;S Niwa;A Chokkalingam;L Cannon-Albright;C Cybulski;Wokolorczyk;W Kluzniak;J Park;T Sellers;HY Lin;WB Isaacs;AW Partin;H Brenner;A Dieffenbach;C Stegmaier;C Chen;EL Giovannucci;J Ma;M Stampfer;KL Penney
Journal / Conference
Nature Genetics 46(10):1103-1109;
Year
2014
Research Committee(s)
Prevention, Screening, and and Surveillance
PMID
PMID25217961
PMC
PMC4383163
Study Number(s)
S0000

Normal young-old men: Results from PREADVISE

Authors
E Abner;R Kryscio;A Caban-Holt;F Schmitt
Journal / Conference
The Journal of Prevention of Alzheimer’s Disease 1(3): 259-60, 2014; Clinical Trials Conf. on Alzheimer’s Disease (Nov. 20-22, 2014, Phil., PA), poster
Year
2014
Research Committee(s)
Prevention, Screening, and and Surveillance
Study Number(s)
S0000A

Lower quality of life scores at baseline are associated with an increased risk of future cognitive impairment: Results from PREADVISE

Authors
R Kryscio;A Abner;A Caban-Holt;FA Schmitt
Journal / Conference
The Journal of Prevention of Alzheimer’s Disease, 1(3):283; 2014;Clinical Trials Conf. on Alzheimer’s Disease (November 20-22, 2014, Phil., PA), poster
Year
2014
Research Committee(s)
Prevention, Screening, and and Surveillance
Study Number(s)
S0000A

Trastuzumab plus adjuvant chemotherapy for human epidermal growth factor receptor 2-positive breast cancer: planned joint analysis of overall survival from NSABP B-31 and NCCTG N9831

Authors
EA Perez;EH Romond;VJ Suman;JH Jeong;G Sledge;CE Geyer;S Martino;P Rastogi;J Gralow;S Swain;E Winer;G Colon-Otero;NE Davidson;E Mamounas;JA Jujewski;N Wolmark
Journal / Conference
Journal of Clinical Oncology Nov 20;32(33):3744-3752
Year
2014
Research Committee(s)
Breast
PMID
PMID25332249
PMC
PMC4226805
Study Number(s)
N9831

Phase III comparison of tamoxifen versus tamoxifen plus ovarian function suppression in premenopausal women with node-negative, hormone receptor-positive breast cancer (E-3193, INT-0142): a trial of the Eastern Cooperative Oncology Group

Authors
AJ Tevaarwerk;M Wang;F Zhao;J Fetting;D Cella;LI Wagner;S Martino;JN Ingle;J Sparano;L Solin;WC Wood;NJ Robert
Journal / Conference
Journal of Clinical Oncology Dec 10;32(35):3948-3958
Year
2014
Research Committee(s)
Breast
Study Number(s)
SWOG-9347 (INT-0142) (E3193)

Consensus report of a joint NCI thoracic malignancies steering committee: FDA workshop on strategies for integrating biomarkers into clinical development of new therapies for lung cancer leading to the inception of "master protocols" in lung cancer

Authors
S Malik;R Pazdur;J Abrams;M Socinski;WT Sause;D Harpole;J Welch;E Korn;C Ullmann;F Hirsch
Journal / Conference
Journal of Thoracic Oncology Oct;9(10):1443-1448
Year
2014
Research Committee(s)
Lung
PMID
PMID25521397
PMC
PMC4165474
Study Number(s)
S1400

Endocrine therapy with or without inhibition of epidermal growth factor receptor and human epidermal growth factor receptor 2: a randomized, double-blind, placebo-controlled phase III trial of fulvestrant with or without lapatinib for postmenopausal women with hormone receptor-positive advanced breast cancer-CALGB 40302 (Alliance)

Authors
HJ Burstein;CT Cirrincione;WT Berry;H Chew;S Tolaney;DE Lake;C Ma;KL Blackwell;E Winer;CA Hudis
Journal / Conference
Journal of Clinical Oncology Dec 10;32(35):3959-3966
Year
2014
Research Committee(s)
Breast
PMID
PMID25348000
PMC
PMC4251959